Influence of Diabetes Mellitus on Outcomes of Patients Undergoing Carotid Artery Stenting: A Systematic Review and Meta-Analysis (Kei, 2025)
Cetinel, Eren; Andrade, Rafael; Labib, Mostafa; Dagostin, Andressa Frankowski; Habiyambere, Ghislain Irakoze; Kei, Him Shun; Madera, Dario.
Annals of Vascular Surgery, Volume 122p635-645 - January 2026
OBJECTIVE: Diabetes mellitus is a well-known risk factor for adverse vascular events, yet its specific influence on carotid artery stenting (CAS) outcomes remains unclear. This study aims to determine if diabetes increases perioperative risks after CAS.
METHODS: A systematic review and meta-analysis compared diabetic vs. non-diabetic CAS patients. We searched PubMed, Embase, Scopus, and Cochrane Library for English cohort studies reporting outcomes by diabetic status. Primary outcome was perioperative stroke; secondary included transient ischemic attack (TIA), myocardial infarction (MI), death, restenosis, and stroke/death composite. Data were pooled using random-effects models. Heterogeneity was quantified by I2, and publication bias was assessed with Egger's regression.