Prevalence, associated factors, and outcomes of behavioural and psychological symptoms of dementia in acute hospitals: asystematic review and meta-analysis (Sampson, 2025)
Kanthee Anantapong, Aimorn Jiraphan, Warut Aunjitsakul, Katti Sathaporn, Nisan Werachattawan, Teerapat Teetharatkul, Pakawat Wiwattanaworaset, Nathan Davies, Elizabeth Lesley Sampson
Alzheimer's & Dementia. 21 Suppl 3:e096052, 2025 Dec.
Acute hospital care can be complicated by behavioural and psychological symptoms of dementia (BPSD), yet the evidence in this setting is diverse. Our study aimed to assess BPSD prevalence in acute hospitals and investigate associated factors,management strategies, and outcomes (PROSPERO: CRD42023406294).Method: We performed a systematic review and meta-analysis, searching Cochrane Library, MEDLINE, and PsycINFO for studies reporting BPSD prevalence in older dementia patients during acute hospital stays (until 5 March 2024). We employed independent double-review processes for study selection and data extraction. Twelve BPSD symptoms were analysed using the Neuropsychiatric Inventory Questionnaire(NPI) and Behavioural Pathology in Alzheimer’s Disease (BEHAVE-AD) scales. We summarised risk factors, treatments, and outcomes, and conducted meta-analyses to synthesise findings.